Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0335425
PubChem CID
Molecular Formula
C16H17N7O
Molecular Weight
323.36 g/mol
Synonyms/Alias
[CHEMBL4440217; BDBM50532009]
InChI Key
ILALNWYMYDFPFR-UHFFFAOYSA-N
InChI
InChI=1S/C16H17N7O/c1-11-9-14(23(19-11)13-7-8-13)17-15(24)10-22-20-16(18-21-22)12-5-3-2-4-6-12/h2-6,...
IUPAC Name
N-(2-cyclopropyl-5-methylpyrazol-3-yl)-2-(5-phenyltetrazol-2-yl)acetamide
CAS Number
N/A (Not available)

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

41 44 0 0 0 0 0 0 0 0999 V2000
-3.6865 1.5244 -3.0840 C 0 0 0 0 0 0 0 0 0 0 0 0
-3.4896 0.7074 -1.8517 C 0 0 0 0 0 0 0 0 0 0 0 0
-4.4389 0.528...

Experimental Data

Activity Data

Target Ion Channel
ATP sensitive inward rectifier potassium channel 11/SUR1
Uniprot Accession Number
Function
Blocker
Species
Rattus norvegicus (Rat)
IC50
IC50: 42000 nM
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
pH 7.3
Holding Potential
Not specified
Temperature
37 °C
Test Method
Flux assay (Thallium ion)
Test Species
Not specified

Binding Information

Binding Site
Not specified
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
24
Rotatable Bonds
5
logP
1.8186
Complexity
87.1177
TPSA (Ų)
90.52
H-Bond Donors
1
H-Bond Acceptors
7
Ring Count
4
New Search